13
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Computer Determination and Comparison of the Compression Behaviour of Powder Mixtures

, &
Pages 1869-1884 | Published online: 20 Oct 2008
 

Abstract

The aim of this work is to analyse the forces measured and stored during compression by using a computer.

We propose to calculate a “tabletibility index” which is very useful to classify the materials according to their capacity to give proper tablets by direct compression. We can also simulate the energy cycles in chosen experimental conditions, as it is not possible to compare cycles if the experimental conditions are not the same, which is very difficult to obtain.

In addition, this program calculates a “cohesion index” which is a dimensionless number. With this program and this cohesion index, it is possible to define the behaviour of different powder mixtures during compression very accurately. This is very useful to compare a batch to a reference as far as quality control, process control and formulation are concerned.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.