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Research Article

Heckel Plots as Indicators of Elastic Properties of Pharmaceuticals

Pages 1903-1912 | Published online: 20 Oct 2008
 

Abstract

In this study the usefulness of different kind of Heckel treatments to describe the elastic properties of the compressed materials was evaluated. Two methods were used to find the values for Heckel function, namely, tablet-in-die method and ejected tablets method. The slope values were calculated by means of the first derivative of the Heckel function. The reliable conclusions from the total elastic recovery were possible to obtain using the reciprocal of the difference of the Heckel upward plot slopes obtained from the two methods used-in this study. The downward part of the Heckel plot was noticed to be useful for describing the fast elasticity during the tableting process.

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