![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
A latex which is a polymerized and cross-linked product of hydroxyendblocked polydimethylsiloxane and an alkoxysilane has been evaluated as a controlled release tablet film coating system. With adequate reinforcement of colloidal silica, the silicone elastomer latex formed solid elastomeric free films upon drying. Polyethylene glycols of different molecular weights were incorporated in the coating system to enhance the permeability of the silicone elastomer to hydrophilic and ionic species. Free films derived from the three-component silicone elastomer dispersions were evaluated by various physical and chemical methods with respect to their suitability as an aqueous controlled release film coating system.