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Research Article

Determining the solubility and crystal form of clenbuterol in thin films of eudragit NE30D

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Pages 319-331 | Published online: 20 Oct 2008
 

Abstract

The solubility of the drug clenbuterol in thin films of surfactant-free Eudragit NE30D has been measured. Light microscopy and differential scanning calorimetry were supplemented by a technique based on measurement of the rate of drug release from the films. The clenbuterol crystals had the form of a fractal, as could be shown by a computer simulation of diffusion-controlled aggregation.

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