65
Views
21
CrossRef citations to date
0
Altmetric
Research Article

Characterization of directly Compressible Maltodextrins Manufactured by three different Processes

&
Pages 2335-2358 | Published online: 20 Oct 2008
 

Abstract

Five types of maltodextrins which were physically processed by the methods of spray drying, fluidized bed agglomeration, and roller compaction were compared in terms of their pre-, during and post-compaction properties. The maltodextrins all had relatively high moisture contents, and small surface areas. Intrinsic compaction testing found that the maltodextrins all formed stronger tablets than Fast-Flo lactose, and had longer disintegration times which were found to be insensitive to pressure. The roller compacted material had the most fragmentary behavior of the five types of maltodextrins examined. Dissolution testing showed that the maltodextrins had longer release rates than Emdex or Fast-Flo lactose, however the maltodextrin formulations were able to pass a modified USP dissolution test.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.