Multiple Myeloma Lesion Detection With Whole Body CT Versus Radiographic Skeletal Survey

Abstract

Objective: To compare accuracy of CT versus radiographs in detecting myeloma lesions. Materials and Methods: Retrospective review of patients who were simultaneously evaluated with radiographs and PET/CT scans. Two radiologists independently assessed each modality. Results: Total number of lesions detected with CT was 968 versus 248 for radiographs (p < .001). Nine patients (18%) had no lesions on either CT or radiographs. Of the remaining 42 patients, 39 had more lesions on CT. CT could have resulted in upstaging of disease in 31 cases (61%). Conclusion: CT is superior for detecting myeloma lesions.

Keywords: :

• Cost effectiveness research
• Detection/diagnosis
• Myeloma