Prognostic Significance of Mucinous Differentiation of Endometrioid Adenocarcinoma of the Endometrium

Abstract

Using Surveillance, Epidemiology, and End Results database we identified 43,882 (97.0%) women with endometrioid adenocarcinomas and 1,374 (3.0%) with mucinous adenocarcinomas. Women with mucinous tumors were older (P < .0001), more often white (P = .04), and more often to present at advanced stage (P = .001). Survival was similar for both histologies; the hazard ratio for cancer-specific survival for mucinous compared to endometrioid tumors was 0.90 (95% CI, 0.74–1.09) while the hazard ratio for overall survival was 0.95 (95% CI, 0.85–1.07). Five-year survival for stage I mucinous tumors was 89.9% (95% CI, 87.6–91.9%) compared to 89.0% (95% CI, 88.6–89.4%) for endometrioid tumors.

Keywords: :

• Health sciences research
• Other gynecologic tumors
• Ovarian cancer