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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 5, 1988 - Issue 4
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Original Article

Diurnal Variation in the Symptoms of Colds and Influenza

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Pages 411-416 | Received 01 Dec 1987, Accepted 01 Jul 1988, Published online: 07 Jul 2009
 

Abstract

The present research examined diurnal variation in the severity of symptoms of experimentally-induced colds and influenza. Nasal secretion was greatest in the morning, decreased over the day, and then showed a slight increase in the late evening. Colds did not change the average temperature, nor did they alter the temperature rhythm. Similar, negative results were found with alertness ratings.

Influenza B illnesses produced an increase in nasal secretion and systemic effects. The average temperature increased during this illness and subjects reported that they felt more drowsy. Diurnal variation in the severity of local and central symptoms was observed, with nasal secretion and the temperature increase being greatest in the early morning. These results have important implications for the assessment and treatment of the illnesses.

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