Acute Tubular Necrosis Associated with Non-Hemorrhagic Dengue Fever: A Case Report

Abstract

Dengue fever (DF) is an arthropod-born viral infection affecting humans. Dengue viruses are transmitted through the bites of the mosquito Aedes aegypti. Acute renal failure (ARF) is reported in patients who are affected mainly with Dengue hemorrhagic fever (DHF), which is a severe presentation of the disease. We report the case of a 24-year-old Omani female with no past history of particular medical problems. She was referred to our hospital for the further management of acute renal failure. She had clinical features of DF without DHF. The kidney biopsy showed features of acute tubular necrosis (ATN). She had a complete recovery after 25 days and required three sessions of hemodialysis. We conclude that DF even without DHF may lead to ATN and ARF. Clinicians should be aware of this etiology. Treatment is supportive and may require dialysis. The prognosis could be favorable.

Keywords:

• Dengue fever
• acute renal failure
• acute tubular necrosis
• renal biopsy
• hemodialysis

ACKNOWLEDGMENTS

We would like to express our gratitude to Dr Firyal Al Lawati and Dr S. Bawikar for their valuable advice and services. The authors report no funding or sponsorship.