A case of Goodpasture’s syndrome complicating pregnancy with dialysis requiring renal failure responding to plasmapheresis and termination of pregnancy

Abstract

Goodpasture’s syndrome complicating pregnancy is extremely rare and dialysis requiring anti GBM disease with renal recovery is uncommon. We report a case of a 23-year-old primi gravida who presented with Goodpasture’s syndrome during thirteenth week of pregnancy. She was initiated on steroids and cytotoxic drugs along with intensive plasma exchange and alternate day hemodialysis. Her pregnancy was terminated at 15 weeks. Patient improved dramatically with treatment, her renal functions normalized and her Anti GBM antibody titer became negative.

• Anti GBM disease
• crescentic glomerulonephritis
• goodpastures syndrome
• plasmapheresis
• renal failure in pregnancy