![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
The tendency of immune response toward either Th1 or Th2 cytokine pattern can cause a number of pathologic conditions. Multiple sclerosis is postulated to be a Th1-type cell-mediated autoimmune disease. MS14—an Iranian natural product—seems to possess anti-inflammatory properties. Thus, we studied the effect of orally administered MS14 on Th2 cytokines (IL-5 and IL-10) in normal Balb/C mice (100 mg/kg; 5 days). The result indicated that activated splenocytes of MS14 group produced significantly more IL-5 and IL-10 (3–4 times in comparison with control group mice). MS14 could upregulate Th2 cytokine and thereby it may possess immunoregulatory properties probably useful in treatment of some diseases.
Acknowledgement
The authors thank Mr. Davood Jamali for carry out ELISA tests.
Declaration of interest
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.