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Journal of Liposome Research Volume 4, 1994 - Issue 1
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Research Article

Human Stratum Corneum Lipid-Based Liposomes (hSCLLs)

Juergen Lasch Department of Biochemistry, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Halle, Germany
,
Ute Schmitt Department of Biochemistry, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Halle, Germany
,
Brigitte Sternberg Institute of Ultrastructural Research, Medical Faculty, Friedrich-Schiller-University, Jena, Germany
&
Rolf Schubert Department of Pharmacy, Eberhard-Karls-University, Tübingen, Germany
Pages 93-106 | Published online: 28 Sep 2008
 
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Abstract

Liposomes were prepared from total lipids extracted from the stratum corneum of human skin. They were studied with respect to size distribution, morphology, phase transitions and marker efflux. Peculiarities of phase transition and morphology are in keeping with the special lipid composition of the horny layer.

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