A Case of Rapid Progression and Vision Loss in a Patient with Primary Intraocular Lymphoma

Abstract

Purpose: To describe an atypical case of primary intraocular lymphoma (PIOL) with rapid progression leading to vision loss and death.

Methods: A 71-year-old woman with a history of PIOL presented with a sudden decline in vision. MRI, CSF cytology, and ocular examination 2 months prior were unremarkable.

Results: Repeat MRI of the brain and orbits at this time revealed a 0.8 × 2.4-cm lesion of the left choroid plexus. LP revealed rare atypical B cells. The patient rapidly deteriorated and died a month later.

Conclusion: Recognition of the potential for rapid progression and mortality in patients with PIOL is essential.

KEYWORDS::

• Primary intraocular lymphoma
• progression
• sudden
• rapid

ACKNOWLEDGMENTS

This study was supported by the NEI intramural research program.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.