Intravascular Lymphoma Mimicking a Vogt-Koyanagi-Harada Disease

Abstract

Purpose: To report a case of intravascular lymphoma (IVL) mimicking a Vogt-Koyanagi-Harada disease (VKH).

Design: Case report.

Methods: A 38-year-old man was referred for blurred vision, headache, and hearing loss. Examination demonstrated vitritis and subretinal detachments in each eye. Cerebral fluid analysis showed lymphocytic meningitis. Cerebral MRI was normal. A diagnosis of VKH disease was made.

Results: Steroid treatment was introduced, after which all symptoms disappeared. Six months later, the patient returned with paraplegia and confusion. Cerebral MRI revealed hypodense periventricular lesions. A stereotaxic biopsy confirmed the diagnosis of IVL. The patient died a few months later.

Conclusion: IVL may have many revealing aspects, including ophthalmologic symptoms.

Keywords::

• exudative retinal detachment
• intravascular lymphoma
• meningitis
• uveitis
• Vogt-Koyanagi-Harada disease

ACKNOWLEDGMENTS

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.