Topical Podophyllum-induced Toxic Anterior Uveitis

Abstract

Objective: To report a case of toxic anterior uveitis probably secondary to the use of topical podophyllum.

Design: Case report, interventional.

Methods: The authors present a 78-year-old male with acute anterior uveitis that developed within a couple of hours of application of topical podophyllum. In vivo confocal microscopy showed unique findings that disappeared following treatment with topical steroids alone. The patient reapplied podophyllum 2 months later and a recurrence of uveitis was noted.

Results: A score of 7 was obtained using the adverse drug reaction probability scale, suggesting that the anterior uveitis is a probable adverse reaction to topical podophyllum.

Conclusions: Anterior uveitis may occur after topical application of podophyllum.

Keywords::

• anterior uveitis
• podophyllum
• topical
• toxic
• wart

ACKNOWLEDGMENTS

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.