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Abstract
Purpose: To describe patients with uveitis and common variable immunodeficiency (CVID).
Design: Retrospective observational case series.
Methods: Retrospective review of patients with uveitis and CVID, specifically focusing on clinical presentation and treatment.
Results: Three patients with CVID and uveitis were identified. All patients had chronic anterior uveitis. Two required systemic immunosuppression to control uveitis, with one of these patients relapsing after discontinuation of immunoglobulin therapy. One improved on topical steroid therapy; however, follow-up on this patient did not extend beyond 4 months.
Conclusions: CVID can be associated with chronic anterior uveitis. Patients presenting with uveitis should be questioned about frequent infections and autoimmune disorders as part of the uveitis evaluation.
ACKNOWLEDGMENT
This publication is supported by an unrestricted grant from Research to Prevent Blindness, New York, New York (DAG). The sponsor had no role in the design or conduct of this research.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.