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Abstract
Purpose: To describe a case of spontaneous dissociation of a fluocinolone acetonide implant (Retisert) 5 years following implantation.
Design: Case report.
Methods: A patient with chronic uveitis underwent placement of a fluocinolone acetonide implant in the right eye in 2006. The patient’s inflammation was well controlled and did not recur, so the device was not replaced.
Results: Five years after implantation, the patient presented with a new complaint of a shadow in his vision. The drug pellet was found to have separated spontaneously from the anchoring strut and was floating in the vitreous. Pars plana vitrectomy was performed with removal of the drug pellet, and the anchoring strut was left in place.
Conclusions: Spontaneous intraocular dissociation of a fluocinolone acetonide implant (Retisert) can occur years after placement, in the absence of trauma or other risk factors. Surgeons and patients must be aware of this potential complication as the implants age.
ACKNOWLEDGEMENT
This study was supported by That Man May See, Inc., and Research to Prevent Blindness.
Declaration of interest: All authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.