Evaluation of Corneal Parameters with Scheimpflug Imaging in Patients with Rheumatoid Arthritis

Abstract

Purpose: To evaluate corneal parameters of rheumatoid arthritis (RA) patients by Pentacam-HR.

Methods: Seventy RA patients and 100 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both RA and control groups were divided into two subgroups as dry eye (DE) (Schirmer test with topical anesthesia (STA) ≤ 5 mm) and without DE (STA > 5 mm).

Results: Pachymetric measurements and the mean corneal volume were significantly lower in RA group (p < 0.001). Disease duration was negatively correlated with pachymetric measurements in RA group. Pachymetric measurements and corneal volume of RA patients with DE were significantly lower than all the other subgroups. Control subgroups with or without DE were similar in pachymetric measurements and corneal volume.

Conclusions: The results suggest that RA patients have thinner corneas compared to control subjects that may be affected by disease duration. Furthermore, coexistence of DE and RA seems to aggravate the thinning of cornea as well.

• Corneal thickness
• corneal volume
• dry eye
• Pentacam-HR
• rheumatoid arthritis