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Ocular Immunology and Inflammation Volume 22, 2014 - Issue 1
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Original Article

Syphilitic Outer Retinopathy

Breno R. LimaNational Eye Institute, National Institutes of Health Bethesda, MarylandUSA
, MD,
Efrem D. MandelcornDepartment of Ophthalmology & Vision Sciences, University of Toronto, Toronto, Ontario, Canada
, MD,
Nupura BakshiDepartment of Ophthalmology & Vision Sciences, University of Toronto, Toronto, Ontario, Canada
, MD,
Robert B. NussenblattNational Eye Institute, National Institutes of Health Bethesda, MarylandUSA
, MD, MPH &
H. Nida SenNational Eye Institute, National Institutes of Health Bethesda, MarylandUSACorrespondence[email protected]
, MD, MHS
Pages 4-8 | Received 04 Jul 2013, Accepted 03 Sep 2013, Published online: 30 Oct 2013
 
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Abstract

Purpose: To present ocular syphilis masquerading as an outer retinopathy. Methods: Retrospective case series, including 2 patients with features of acute zonal occult outer retinopathy (AZOOR) complex diseases. Results: Laboratory results confirmed the diagnosis of syphilis in the 2 cases. Therapy with intravenous penicillin led to an improvement in symptoms, visual acuity, and ancillary testing. Conclusions: The protean ophthalmic presentations of syphilis are well known. However, AZOOR-like presentation has not been described previously. This atypical outer retinopathy should alert physicians to keep syphilis in the differential diagnosis of any inflammatory disorder.

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