Leydig cell tumour of the ovary localised with Positron Emission Tomography/Computed Tomography

Abstract

Androgen-producing ovarian tumours can lead to assessment difficulties because of their small size. We present a case of virilising steroid cell ovarian tumour in a 41-year-old woman localised with Fluorine-18-Deoxyglucose Positron Emission Tomography/Computed Tomography (¹⁸FDG-PET/CT). Although the biochemical evaluation pointed to an ovarian source of androgen, diagnostic attempts to localise the source of hyperandrogenism with transvaginal ultrasound (US), and magnetic resonance imaging (MRI) of pelvis failed. Additional evaluation with ¹⁸FDG-PET/CT showed an increased uptake in the right ovary. A laparoscopic right oophorectomy was performed and histopathology examination revealed a 1.2-cm Leydig cell tumour. The patient showed regression of clinical signs.

Keywords:

• Leydig cell tumour
• ovary
• testosterone
• androblastoma
• PET

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.