The use of portable CO₂ incubator for cross-border shipping of embryos in an international egg donation program

Abstract

Two groups of egg recipients were treated, one in situ (165 patients; 195 cycles) and one after cross-border embryo transportation (340 cycles; 340 cycles) using mobile CO₂ incubator. The positive pregnancy rate per cycle was 199/340 (58.6%) and 99/195 (50.7%) in the transportation and the traveling group, respectively (NS). The clinical pregnancy rate (fetal heart beat) was 48.1 and 43.1% per embryo transfer cycle, respectively (NS) and the delivery rate was 44.1 and 35.9% per embryo transfer cycle, respectively (p = 0.01). Long distance transportation of human pre-implantation embryos using portable CO₂ incubator is safe and do not jeopardize their developmental potential.

Chinese abstract

两组受试者，一组在国内（165名患者，195个周期），一组通过CO₂培养箱进行跨境胚胎运输（340名患者，340个周期）。每个周期的阳性妊娠率分别为运输组199/340(58.6%)、国内移植组99/195 (50.7%)（差别无统计学意义）。每个胚胎移植周期临床妊娠率（可见胎心）分别为48.1%和43.1%（差别无统计学意义）。每个胚胎移植周期分娩率为44.1%和35.9%（P=0.01）。使用便携式CO₂孵箱对人植入前胚胎进行长途运输是安全的，并不会危及其发育潜能。

• Egg donation
• embryo culture
• embryo transportation
• in vitro fertilization