The Russian experience of autotransplantation of vitrified ovarian tissue to a cancer patient

Abstract

To present preliminary results of autotransplantation of vitrified human ovarian tissue to thyroid cancer patient, who underwent radioiodine treatment, performed at MRRC. Cryopreservation of ovarian tissue is increasingly used in the multi-modality treatment of cancer patients. The main purpose of ovarian tissue cryopreservation is to preserve the patient’s fertility before gonadotoxic chemo- and radiotherapy. In 2012, the first orthotopic transplantation of ovarian tissue to the patient previously treated with radioactive iodine was performed at the MRRC in Russia. Monitoring changes in the ovarian reserve allowed us to assess efficacy of the orthotopic transplantation. The results demonstrated a trend to recovery of the patient’s reproductive potential.

• Cancer patient
• fertility preservation
• ovarian reserve
• tissue vitrification
• transplantation