The effects of polycystic ovary syndrome on gestational diabetes mellitus

Abstract

The aim of this study was to explore the inter-relationship between polycystic ovary syndrome and gestational diabetes mellitus, and demonstrate maternal and fetal outcomes. This was a case-control study in 1360 pregnant women who received a diagnosis of gestational diabetes mellitus between 24 and 28 weeks of gestational age. Among all diagnosed with gestational diabetes mellitus, 150 pregnant women had received a polycystic ovary syndrome, and 160 women who did not have polycystic ovary syndrome were designated as controls. The incidence of pregnancy-induced hypertension was 26.3% and 12% in the case and control groups, respectively. Preeclampsia was seen at an incidence of 12% and 6% in case and in control groups, respectively. The difference in neonatal hypoglycemia between the two groups was statistically significant, with an incidence of 17% and 5% in the case and in control groups, respectively. This study demonstrated that the presence of polycystic ovary syndrome along with gestational diabetes mellitus increases the risk of pregnancy induced hypertension by 2.4 fold, preeclampsia by 2 fold and neonatal hypoglycemia by 3.2 fold, compared to gestational diabetes mellitus alone.

Chinese abstract

该研究的目的是为了探讨多囊卵巢综合征和妊娠期糖尿病的关系及母儿结局。该项病例对照研究包含1360名在孕24-28周诊断为妊娠期糖尿病的孕妇。在所有已诊断妊娠期糖尿病的孕妇中，150名孕妇既往诊断为多囊卵巢综合征，160名非多囊卵巢综合征孕妇作为对照组。妊娠期高血压疾病的发生率在病例组和对照组分别为26.3%和12%。子痫前期的发生率在病例组和对照组分别为12%和6%。两组新生儿低血糖的发生率有显著性差异，在病例组和对照组分别为17%和5%。该研究表明多囊卵巢综合征合并妊娠期糖尿病与单纯妊娠期糖尿病相比，妊娠期高血压疾病的风险增加2.4倍，子痫前期的风险增加2倍，新生儿低血糖的风险增加3.2倍。

• Diabetes
• polycystic ovary syndrome
• pregnancy

Declaration of interest

Author declares no conflict of interest.