Autoimmune progesterone urticaria

C. Vasconcelos Department of Dermatology and Venereology, University Hospital of São João, Porto, Portugal

P. Xavier Department of Gynecology and Obstetrics, University Hospital of São João, Porto, Portugal

A. P. Vieira Department of Dermatology and Venereology, University Hospital of São João, Porto, Portugal

M. Martinho Department of Gynecology and Obstetrics, University Hospital of São João, Porto, Portugal

J. Rodrigues Immunoallergology Unit, University Hospital of São João, Porto, Portugal

A. Bodas Department of Immunology, University Hospital of São João, Porto, Portugal

M. A. Barros Department of Dermatology and Venereology, University Hospital of São João, Porto, Portugal

J. Mesquita-guimarães Department of Dermatology and Venereology, University Hospital of São João, Porto, Portugal

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Abstract

Autoimmune progesterone dermatitis is a rare cutaneous disorder characterized by recurrent and cyclic skin eruption with variable morphology, occurring during the luteal phase. A case of autoimmune progesterone urticaria in a 47-year-old woman is reported. An intradermal progestin test revealed a strong reactivity against this hormone. Treatment with tamoxifen and leuprolide acetate induced only a partial remission of urticaria. Bilateral oophorectomy was performed with absolute clearing of cutaneous lesions.

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Autoimmune progesterone urticaria

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Autoimmune progesterone urticaria

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