Hormone replacement therapy and successful pregnancy in a patient with premature ovarian failure

Abstract

Premature ovarian failure (POF), premature ovarian insufficiency, premature menopause or hypergonadotropic hypogonadism, a serious life-changing condition that affects young women, remains an enigma and the researcher's challenge. In the present article we described a case of singleton pregnancy in a 33-year-old patient, presenting with POF and treated with hormone replacement therapy. Twenty months later this therapy led to maturation of one follicle, recruitment and fertilisation of the residual oocyte and spontaneous pregnancy ensued. A normal infant was delivered by cesarean section.

Keywords:

• Premature ovarian failure
• hormone replacement therapy
• pregnancy

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.