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Gynecological Endocrinology Volume 1, 1987 - Issue 3
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Original Article

In situ hybridization identifies renin mRNA in the rat corpus luteum

A. Lightman Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, USA
,
C. F. Deschepper Department of Physiology, University of California, San Francisco, USA
,
S. H. Mellon Department of Physiology, University of California, San Francisco, USA
,
W. F. Ganong Department of Physiology, University of California, San Francisco, USA
&
F. Naftolin Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, USA
Pages 227-233 | Published online: 07 Jul 2009
 
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Abstract

All components of the renin-angiotensin system (RAS), including angiotensinogen messenger RNA (mRNA), renin-like activity (RLA), renin mRNA, angiotensin II (A II) immunoreactivity and angiotensin converting enzyme, have been found in the whole rat ovary and A II receptors have recently been localized to ovarian follicles. Our study was designed to test further which part of the ovary can produce renin.

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