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Case Reports

Thrombocytosis secondary to chronic lead poisoning

Pages 297-299 | Received 08 Nov 2009, Accepted 11 Jan 2010, Published online: 02 Mar 2010
 

Abstract

We report a case of total hyperpigmentation of the skin, severe itching, muscle weakness and thrombocytosis. Laboratory investigation showed white blood cell (WBC) 8.2 × 106/L, Hb 125 g/L, platelets 1221 × 106/L and urinary lead after DMSA mobilization test 2684 mcg/g creatinine (normal <5). Chelation therapy with DMSA resulted in complete recovery of the hyperpigmentation, itching and thrombocytosis. Lead poisoning should be considered in the differential diagnosis of obscured thrombocytosis.

Acknowledgment

We acknowledge Prof. AMA Gader for his critical review of this article.

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