Possible indications for vitamin D₃ analogues in conditions other than psoriasis vulgaris

Pcm van de Kerkhof Department of Dermatology, University Hospital Nijmegen, The Netherlands

M Wittenhorst Department of Dermatology, University Hospital Nijmegen, The Netherlands

Mjp Gerritsen Department of Dermatology, University Hospital Nijmegen, The Netherlands

Emgj de Jong Department of Dermatology, University Hospital Nijmegen, The Netherlands

Gph Lucker Department of Dermatology, University Hospital Nijmegen, The Netherlands

Pm Steylen Department of Dermatology, University Hospital Nijmegen, The Netherlands

Abstract

Vitamin D₃ analogues interfere with various aspects of cutaneous inflammation, keratinization and epidermal proliferation, and are effective in chronic plaque psoriasis. Recently their clinical efficacy has been investigated in other skin disorders. So far, the vitamin D₃ analogue calcipotriol has proved to be effective in pustular psoriasis, congenital ichthyosis, inflammatory linear verrucous epidermal naevus, Graver's disease and pityriasis rubra pilaris. Information on the effect of other vitamin D₃ analogues in these conditions is limited.

Key Words:

Vitamin D₃ analogues

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Possible indications for vitamin D₃ analogues in conditions other than psoriasis vulgaris

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Possible indications for vitamin D₃ analogues in conditions other than psoriasis vulgaris