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Abstract
Objective: The aim was to investigate whether the daily intake of special nutrients, enriched with supplements from natural origins, has any effect on blood parameters.
Design and subjects: In this double-blind placebo-controlled clinical trial, 80 healthy subjects (mean age 26.3 years) were statistically assigned to two groups. Group I had to eat two special yoghurt and bread products a day. The other probands represented the control group (II).
Setting: Plasma concentrations of blood parameters were measured at the beginning and at the end of the study, and dietary intake was calculated.
Results: In group I, total cholesterol decreased. This was due to a significant drop of low-density lipoprotein-cholesterol from 106.0 to 99.0 mg/dl. A significant reduction of the apolipoprotein B and an increase of vitamin A in group I were also observed.
Conclusion: Regular intake of specially fortified food influences parameters, especially lipids and lipoproteins.
Acknowledgements
The study was planned by K.W., for the most part, and H.K.W., who was mainly responsible for the correct processing of the study. The laboratory analysis was carried out under observation of K.H. and evaluations of the 3-day dietary diaries and calculations were done by I.K. and M.K. H.K.W. contributed to the tables and the data content of the paper.
Declarations of interests: The study was supported by a research grant provided by ‘vis Vitalis-Salzburg’. One position for a physician (H.W.) and for a technician (C.W.) has been supported by the company.