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Abstract
The objective of the present study was to determine the effectiveness of a soluble dietary fiber, NUTRIOSE®, on body weight, body composition, energy intake and hunger in overweight Chinese men. The volunteers were randomized in double-blind fashion to 250 ml fruit juice supplemented with NUTRIOSE® (Test, n = 60) or a maltodextrin (Control, n = 60) at a dosage of 17 g twice daily for 12 weeks. Body weight, body composition were performed at 0, 4, 8 and 12 weeks while daily energy intake and hunger were assessed every 3 days. Test subjects had reductions in body weight (1.5 kg, P < 0.001), body mass index (0.5 kg/m2, P < 0.001) and body fat percentage (0.3%, P < 0.001) versus Controls. NUTRIOSE® supplementation resulted in a lower daily energy intake (3,079 kJ/day, P < 0.001) with group differences noted as early as 3 days. Test subjects reported less hunger across the study period versus Controls (P < 0.01). NUTRIOSE® supplementation for 12 weeks results in body composition improvements and reduces body weight, energy intake and hunger in overweight men.
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Declarations of interests
The authors thank Charlie Zhang, M.D. and Kelly Zhang, R.N. for study management assistance. Michael Shleifer, Ph.D. is gratefully acknowledged for his assistance in the design and performance of the study. Roquette Frères (Lestrem, France) provided financial support for this clinical trial. Sprim Advanced Life Sciences (San Francisco, CA, USA) helped with study planning, conduct, and analysis and with manuscript development.