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Research Article

A detailed comparative study between chemical and bioactive properties of Ganoderma lucidum from different origins

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Pages 42-47 | Received 09 May 2013, Accepted 02 Aug 2013, Published online: 11 Sep 2013
 

Abstract

A detailed comparative study on chemical and bioactive properties of wild and cultivated Ganoderma lucidum from Serbia (GS) and China (GCN) was performed. This species was chosen because of its worldwide use as medicinal mushroom. Higher amounts of sugars were found in GS, while higher amounts of organic acids were recorded in GCN. Unsaturated fatty acids predominated over saturated fatty acids. GCN revealed higher antioxidant activity, while GS exhibited inhibitory potential against human breast and cervical carcinoma cell lines. No cytotoxicity in non-tumour liver primary cell culture was observed for the different samples. Both samples possessed antibacterial and antifungal activities, in some cases even better than the standard antimicrobial drugs. This is the first study reporting a comparison of chemical compounds and bioactivity of G. lucidum samples from different origins.

Acknowledgements

We are grateful to Ana Zupanc and Zoran Stevanović for providing us fresh material of G. lucidum mushroom.

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