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Research Article

The Biology of Pneumocystis Carinii

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Pages 191-216 | Published online: 25 Sep 2008
 

Abstract

Pneumocystis carinii was first described in the lungs of guinea pigs during studies of experimental American trypanosomiasis by Chagas in 1909.1 The organism was thought to represent a variant in the sexual life cypcle of Trypanosoma cruzi. Carini found the organism in trypanosome-infected rats, but it was not until 1912 that the organisms were recognized as belonging to a new genus and assigned the name of Pneumocystis carinii when Delanöes identified identical forms in the lungs of rats which had not been infected with trypanosomes.2

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