Genomic Structure of Mouse and Human Genes for DNA-PKcs Interacting Protein (KIP)

Atsushi Hattori Genome Research Group, National Institute of Radiological Sciences, 4–9–1 Anagawa, Inagc-ku, Chiba, 263-8555, Japan; Biotechnology and Medical Engineering Field, Aisin Cosmos R&D Co., Ltd., 5–50 Hachiken-cho, Kariya, Aichi, 448-8650, Japan

Naohiko Seki Genome Research Group, National Institute of Radiological Sciences, 4–9–1 Anagawa, Inagc-ku, Chiba, 263-8555, Japan; Laboratory of Gene Function II, Kazusa DNA Research Institute, Yana 1532–3, Kisarazu, Chiba, 292-0812, Japan

Akiko Hayashi Genome Research Group, National Institute of Radiological Sciences, 4–9–1 Anagawa, Inagc-ku, Chiba, 263-8555, Japan

Sumie Kozuma Genome Research Group, National Institute of Radiological Sciences, 4–9–1 Anagawa, Inagc-ku, Chiba, 263-8555, Japan

Toshiyuki Saito Genome Research Group, National Institute of Radiological Sciences, 4–9–1 Anagawa, Inagc-ku, Chiba, 263-8555, JapanCorrespondence[email protected]

Abstract

DNA-dependent protein kinase (DNA-PK) is a nuclear protein serine/threonine kinase in a wide variety of vertebrate species and it has a role in the DNA repair and recombination process of lymphoid development. DNA-PK is composed of a large catalytic subunit (DNA-PKcs) and DNA-binding protein, Ku. Recently, the mouse and human DNA-PKcs interacting proteins (Kip/KIP) have been reported. In this report, we have determined the complete genomic structure of mouse and human Kip/KIP genes. The total length of mouse Kip gene and human KIP gene are approximately 5.7 kb and 3.6 kb in genomic DNAs, respectively. Both of genes consist of 7 exons.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Genomic Structure of Mouse and Human Genes for DNA-PKcs Interacting Protein (KIP)

Information for

Open access

Opportunities

Help and information

Genomic Structure of Mouse and Human Genes for DNA-PKcs Interacting Protein (KIP)

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature