Identification of C15orf5, a Heart-Enriched Transcript on Chromosome 15q23-q24

Laura Carim-Todd Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Hospital Duran i Reynals, Av. Gran Via sin km 2,7 L'Hospitalet de Llobregat, 08907, Barcelona, Spain

Lauro Sumoy Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Hospital Duran i Reynals, Av. Gran Via sin km 2,7 L'Hospitalet de Llobregat, 08907, Barcelona, SpainCorrespondence[email protected]

Nuria Andreu Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Hospital Duran i Reynals, Av. Gran Via sin km 2,7 L'Hospitalet de Llobregat, 08907, Barcelona, Spain

Xavier Estivill And Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Hospital Duran i Reynals, Av. Gran Via sin km 2,7 L'Hospitalet de Llobregat, 08907, Barcelona, Spain

Monica Escarceller Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Hospital Duran i Reynals, Av. Gran Via sin km 2,7 L'Hospitalet de Llobregat, 08907, Barcelona, Spain

Abstract

We have isolated C15orf5, a novel human gene lacking homology to any known protein. The C15orf5 gene encodes a transcript of 1, 519 nt with an ORF of 94 amino acids and a predicted protein size of 11.5 kDa. Northern blot analysis showed enhanced expression of C15orf5 in heart. C15orf5 was mapped to chromosome 15q23-q24 using the Stanford TNG4 Radiation Hybrid panel.

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Identification of C15orf5, a Heart-Enriched Transcript on Chromosome 15q23-q24

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Identification of C15orf5, a Heart-Enriched Transcript on Chromosome 15q23-q24

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