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Abstract
The DNA sequence of an internal EcoRI fragment in the large subunit ribosomal RNA gene from the myxomycete Physarum polycephalum, strain M3C, has been determined. This ribosomal DNA fragment contain two group I introns. Sequence heterogeneity in the two introns and in the coding region of the ribosomal RNA were identified upon comparison to the strain PPO-1 sequence. The nature of the sequence variations is discussed.