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Letter to the Editor

Next-generation sequencing identifies a novel ELAVL1–TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208

Adriana E. TronOncology iMed, AstraZeneca, Waltham, MA, USA; Correspondence[email protected]

Erika K. KeetonOncology iMed, AstraZeneca, Waltham, MA, USA; ;N-of-One, Inc, Lexington, MA, USA;

Minwei YeOncology iMed, AstraZeneca, Waltham, MA, USA;

Matias Casas-SelvesOncology iMed, AstraZeneca, Waltham, MA, USA; ;Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, Canada;

Huawei ChenOncology iMed, AstraZeneca, Waltham, MA, USA;

Keith S. DillmanOncology iMed, AstraZeneca, Waltham, MA, USA;

Rosemary E. GaleDepartment of Haematology, University College London Cancer Institute, London, UK;

Chloe StengelDepartment of Haematology, University College London Cancer Institute, London, UK;

Michael ZindaOncology iMed, AstraZeneca, Waltham, MA, USA;

David C. LinchDepartment of Haematology, University College London Cancer Institute, London, UK;

Zhongwu LaiOncology iMed, AstraZeneca, Waltham, MA, USA;

Asim KhwajaDepartment of Haematology, University College London Cancer Institute, London, UK;

Dennis HuszarOncology iMed, AstraZeneca, Waltham, MA, USA; ;Oncology Drug Discover Unit, Takeda Pharmaceuticals International Co, Cambridge, MA, USA

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Acknowledgments

We wish to thank Farzin Gharahdaghi for mass spectrometry, Meghan Scarpitti, Suping Wang and Kelly Theriault for technical assistance and Shaun Grosskurth for bioinformatics contributions.

Potential conflict of interest

Disclosure forms provided by the authors are available with the full text of this article at http://dx.doi.org/10.3109/10428194.2016.1171861.

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Next-generation sequencing identifies a novel ELAVL1–TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208

Potential conflict of interest

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Next-generation sequencing identifies a novel ELAVL1–TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208

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Potential conflict of interest

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