Advanced search
Publication Cover
Leukemia & Lymphoma Volume 6, 1992 - Issue 2
Submit an article Journal homepage
7
Views
5
CrossRef citations to date
0
Altmetric
Original Article

New Directions in the Biology and Therapy of Chronic Myeloid Leukemia

Albert B. Deisseroth The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Wei Zhang The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Ying Cha The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Tianying Yuan The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Hanchun Chen The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Simon Sims The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Andrzej Wedrychowski The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Pei-Qing Gao The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Laurel Huston The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Marylynne Filaccio The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
David Claxton The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Steven Kornblau The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Elizabeth Johnson The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
O. M. Zack Howard The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Borje Andersson The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Auro Del Giglio The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Laurent Gressot The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Hagop Kantarjian The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Moshe Talpaz The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Issa Khouri The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Richard Champlin The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Michael Andreeff The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Eugenia Gaozza The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
David Seong The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Soon-Pal Suh The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Debra Ellerson The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
,
Guiying Hu The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
&
Marian Chou The Department of Hematology and the Department of Clinical Immunology and Biological Therapy, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA
 show all
Pages 89-95 | Received 30 Jun 1991, Published online: 01 Jul 2009
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Great excitement surrounded the initial discovery of the Philadelphia chromosome translocation and the molecular rearrangement of the abl protooncogene which is generated by this translocation in chronic myelogenous leukemia (CML). In this review, we will discuss how molecular analysis of the biological abnormalities generated in the CML cells by this molecular rearrangement can be applied to new directions in therapy for this disease.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.