Occurrence of a T Cell Lymphoma in a Patient with Chronic Myeloid Leukemia Treated with Alpha Interferon

Béatrice Mahé Service d'Hématologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

Fanny Gaillard Service d'Anatomopathologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

François Labadie Service d'Hématologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

Sophie Papin Service d'Hématologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

Stéphane Letortorec Service d'Hématologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

Philippe Moreau Service d'Hématologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

Jean-Luc Harousseau Service d'Hématologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

Noel Milpied Service d'Hématologie, CHU Hôtel-Dieu, Place Alexis Ricordeau, 44035, Nantes, France

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Abstract

A patient treated by recombinant human alpha interferon for chronic myeloid leukemia developed a T cell lymphoma. The T cell lymphoma cells were demonstrated to be genotypically different from the chronic myeloid leukemia cells. The possible role of interferon therapy in stimulating T cell proliferation is discussed.

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Occurrence of a T Cell Lymphoma in a Patient with Chronic Myeloid Leukemia Treated with Alpha Interferon

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Occurrence of a T Cell Lymphoma in a Patient with Chronic Myeloid Leukemia Treated with Alpha Interferon

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