The Development of Congestive Cardiac Failure in a Patient with Hairy Cell Leukemia Treated with 2-Chlorodeoxyadenosine

Abstract

Deoxyadenosines are closely related to adenosine and as such, may interfere with the cardiac adenylate cyclase pathway resulting in cardiac dysfunction. We report a rare case of a 42 year old man who developed transient cardiac failure following treatment with 2-CDA for hairy cell leukemia.

Key Words:

• 2-chlorodeoxyadenosine
• hairy cell leukemia
• cardiac failure