Primary Mediastinal B-Cell Lymphoma: Update of its Clinicopathologic Features

M. Paulli Research Unit/Anatomic Pathology Section.

M. Lazzarino Institute of Haemutohgy, I.R.C.C.S. Policlinico S. Matteo, and University of Paviua, Pavia, Italy

U. Gianelli Research Unit/Anatomic Pathology Section.

E. Sträuter Institute of Pathology, University of Ulm, Ulm, Germany

E. Orlandi Institute of Haemutohgy, I.R.C.C.S. Policlinico S. Matteo, and University of Paviua, Pavia, Italy

C. Klersy Research Unit/Anatomic Pathology Section.

A. Viglio Research Unit/Anatomic Pathology Section.

R. Rosso Research Unit/Anatomic Pathology Section.

M. Gambacorta Institute of Pathology, University of Ulm, Ulm, Germany

T. Rousset Service de Maladies du sang, Hôpital Lapeyronie, Montpellier, France

E. Morra Parhology and Haematology sections, Niguarda Hospital, Milan, Italy

T. Lavabre-Bertrand Service de Maladies du sang, Hôpital Lapeyronie, Montpellier, France

C. Bernasconi Institute of Haemutohgy, I.R.C.C.S. Policlinico S. Matteo, and University of Paviua, Pavia, Italy

C. Manegold Thoraxklinik Heidelberg-Rohrbach, Heidelberg, Germany

U. Magrini Research Unit/Anatomic Pathology Section.

P. Möller Institute of Pathology, University of Ulm, Ulm, Germany

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Abstract

The peculiar clinical, histomorphological and biological characteristics of PMBCL are reviewed. Special emphasis is given to the frequent aggressive clinical behaviour of this lymphoma in which conventional prognostic factors seem inadequate to identify high risk cases. The need for new clinical and/or biological prognostic markers is stressed.

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Primary Mediastinal B-Cell Lymphoma: Update of its Clinicopathologic Features

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Primary Mediastinal B-Cell Lymphoma: Update of its Clinicopathologic Features

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