Chronic Eosinophilic Leukemia: Successful Treatment with an Unrelated Bone Marrow Transplantation

N. Basara Clinic of Bone Marrow Transplantation and Hematoloey/Oncology, Idar-Oberstein, Germany

J. Markova Department of Clinical Hematology, University Hospital 3rd Medical Faculty, Charles University, Prague, Czech Republic

B. Schmetzer Clinic of Bone Marrow Transplantation and Hematoloey/Oncology, Idar-Oberstein, Germany

I. W. Blau Clinic of Bone Marrow Transplantation and Hematoloey/Oncology, Idar-Oberstein, Germany

M. G. Kiehl Clinic of Bone Marrow Transplantation and Hematoloey/Oncology, Idar-Oberstein, Germany

M. Bischoff Clinic of Bone Marrow Transplantation and Hematoloey/Oncology, Idar-Oberstein, Germany

D. Kirsten Clinic of Bone Marrow Transplantation and Hematoloey/Oncology, Idar-Oberstein, Germany

A. A. Fauser Clinic of Bone Marrow Transplantation and Hematoloey/Oncology, Idar-Oberstein, GermanyCorrespondence[email protected]

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Abstract

The optimal treatment of eosinophilic leukemia is still uncertain. We report the successful treatment of a 21-year-old patient with eosinophilic leukemia, without cytogenetic abnormalities, by bone marrow transplantation from an unrelated donor. The conditioning regimen for the transplantation consisted of fractionated total body irradiation and cyclophosphamide. Acute GVHD, grade I, post-transplantation was successfully treated. No other severe complications occured. The patient is alive in complete remission 21 months after unrelated bone marrow transplantation.

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Chronic Eosinophilic Leukemia: Successful Treatment with an Unrelated Bone Marrow Transplantation

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Chronic Eosinophilic Leukemia: Successful Treatment with an Unrelated Bone Marrow Transplantation

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