Aplastic Anemia Responsive to Cyclosporine Complicating the Evolution of Polycythemia Vera

Didier Bouscary Service d'Hématologie, Hôital Cochin, Paris

Katayoun Jondeau Service d'Hématologie, Hôital Cochin, Paris

Franck Viguié Laboratoire de Cytogénétique, Hôpital Hôtel Dieu, Paris, France

Simona Zompi Service d'Hématologie, Hôital Cochin, Paris

Michaella Fontenay-roupie Service d'Hématologie, Hôital Cochin, Paris

Marie Catherine Quarre Site Transfusionnel, Hôpital Cochin, Paris

Dominique Vassilief Site Transfusionnel, Hôpital Cochin, Paris

Francois Dreyfus Service d'Hématologie, Hôital Cochin, Paris

Nicole Casadevall Laboratoire d'Hématologie, Hôpital Raymond Poincaré, Garches

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Abstract

We report here a very unusual patient with Polycythemia Vera treated with Pipobroman who developed severe aplastic anemia following administration of the drug. Six months later, because of lack of response, cyclosporine therapy was given there was rapid and complete hematological recovery, highly suggestive of an immune-mediated mechanism, in this case.

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Aplastic Anemia Responsive to Cyclosporine Complicating the Evolution of Polycythemia Vera

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Aplastic Anemia Responsive to Cyclosporine Complicating the Evolution of Polycythemia Vera

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