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Review Article

Multifunctional hybrid-carbon nanotubes: new horizon in drug delivery and targeting

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Pages 294-308 | Received 23 Mar 2015, Accepted 24 May 2015, Published online: 06 Jul 2015
 

Abstract

Carbon nanotubes (CNTs) have emerged as an intriguing nanotechnological tool for numerous biomedical applications including biocompatible modules for the bioactives delivery ascribed to their unique properties, such as greater loading efficiency, biocompatibility, non-immunogenicity, high surface area and photoluminescence, that make them ideal candidate in pharmaceutical and biomedical science. The design of multifunctional hybrid-CNTs for drug delivery and targeting may differ from the conventional drug delivery system. The conventional nanocarriers have few limitations, such as inappropriate availability of surface-chemical functional groups for conjugation, low entrapment/loading efficiency as well as stability as per ICH guidelines with generally regarded as safe (GRAS) prominences. The multifunctional hybrid-CNTs will sparked and open a new door for researchers, scientist of the pharmaceutical and biomedical arena. This review summarizes the vivid aspects of CNTs like characterization, supramolecular chemistry of CNTs–dendrimer, CNTs–nanoparticles, CNTs–quantum dots conjugate for delivery of bioactives, not discussed so far.

Declaration of interest

The authors declare no competing financial interests.

The authors report no conflict of interest related to manuscript.

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