Effect of Revised UPPP Surgery on Ambulatory BP in Sleep Apnea Patients with Hypertension and Oropharyngeal Obstruction

Abstract

This study aimed to investigate the value of the surgery of revised uvulopalatopharyngoplasty (UPPP) on ambulatory blood pressure (BP) in obstructive sleep apnea/hypopnea syndrome (OSAHS) patients with hypertension and oropharyngeal obstruction. A retrospective cohort study was performed in 29 patients with OSAHS and hypertension, who received treatment with revised UPPP surgery. After surgery 1 month, the Apnea-hypopna index (AHI) and body mass index (BMI) significantly decreased (P < 0.05), and mini SpO₂ and mean SpO₂ increased than before (P < 0. 05), but the heart rate showed no significant difference (P > 0.05). In the meantime, compared to pretreatment, nighttime systolic SBP, nighttime diastolic DBP, morning systolic SBP, morning diastolic DBP, 24-h DBP, and 24-h SBP, decreased significantly (P < 0.05), but daytime SBP and daytime DBP showed no significant difference (P > 0.05). The results of this study indicated that the BP in the sleep apnea patients with hypertension might gradually decrease by revised UPPP surgery.

Keywords:

• revised uvulopalatopharyngoplasty
• obstructive sleep apnea/hypopnea syndrome
• hypertension
• ambulatory blood pressure
• oropharyngeal obstruction