Acute Obstructive Apnea Produces Natriuresis in Spontaneously Hypertensive Rats (SHR) by a Renal Nerve-Dependent

Tadeu U. Andrade Department of Pharmacy, University Center of Vila Velha, Vila Velha, Brazil

João V. M. Franquini Department of Pharmacy, University Center of Vila Velha, Vila Velha, Brazil

Antônio M. Cabral Department of Physiological Sciences, Federal University of Espirito Santo, Vitoria, Brazil

Elisardo C. Vasquez Department of Physiology, Federal University of Espirito Santo, Vitoria, Brazil

Maria T. Araújo Department of Physiology, Federal University of Espirito Santo, Vitoria, Brazil

Margareth R. Moysés Department of Physiology, Federal University of Espirito Santo, Vitoria, Brazil

Gláucia R. Abreu Department of Physiology, Federal University of Espirito Santo, Vitoria, Brazil

Nazare S. Bissoli Department of Physiological Sciences, Federal University of Espirito Santo, Vitoria, BrazilCorrespondencenaza@@npd.ufes.br

show all

Abstract

The role of renal nerve in excretion was investigated during acute obstructive apnea (OA) episodes in SHR. The animals (SHR and control, C) were presented for renal denervation (D; CD; SHRD) or undenervation (U; CU; SHRU). Tracheal catheterization was performed to induce OA via its total occlusion. Urine samples were collected every 2 min after 20 s of OA. Obstructive apnea resulted in bradycardia, hypotension, and induced elevations in the urinary measurements in SHRU, but not in CU. Conversely, the denervation increased in CD, but not in the SHRD. Urinary excretion was dependent of renal nerve in SHR during OA

Keywords

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Acute Obstructive Apnea Produces Natriuresis in Spontaneously Hypertensive Rats (SHR) by a Renal Nerve-Dependent

Information for

Open access

Opportunities

Help and information

Acute Obstructive Apnea Produces Natriuresis in Spontaneously Hypertensive Rats (SHR) by a Renal Nerve-Dependent

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature