An Additional LDL-Lowering Effect of Amlodipine; Not Only an Antihypertensive?

Zekeriya ArslanDepartment of Cardiology, Gelibolu Hospital, Canakkale, Turkey

Seyit Ahmet AyDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Murat KaramanDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Mustafa CakarDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, TurkeyCorrespondence[email protected]

Turgay CelikDepartment of Cardiology, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Sevket BaltaDepartment of Cardiology, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Muharrem AkhanDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Hakan SarlakDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Erol ArslanDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Seref DemirbasDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Sait DemirkolDepartment of Cardiology, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Fatih BulucuDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

Kenan SaglamDepartment of Internal Medicine, Gulhane Medical Academy, School of Medicine, Etlik-Ankara, Turkey

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Abstract

Hypertension is a modifiable risk factor for cardiovascular diseases and is associated with several metabolic disorders like dyslipidemia. Higher levels of triglyceride and low-density lipoprotein (LDL) are quite strong factors for the development of cardiovascular diseases. In this study, we investigated the effects of valsartan and amlodipine on the lipid profile in patients with newly diagnosed essential hypertension. We observed a beneficial effect of amlodipine on the lipid profile with a significant reduction of LDL compared to valsartan. In the treatment of hypertension, prior knowledge of the plasma cholesterol levels can be important in antihypertensive drug choice.

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An Additional LDL-Lowering Effect of Amlodipine; Not Only an Antihypertensive?

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An Additional LDL-Lowering Effect of Amlodipine; Not Only an Antihypertensive?

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