Arterial Pressure and Plasma Vasopressin: Regulation by Neurons in the Caudal Ventrolateral Medulla of the Rabbit

Abstract

Experiments in the anesthetized rabbit have demonstrated that the caudal ventrolateral medulla oblongata contains tonically active vasodepressor neurons which are themselves inhibited by GABAergic and glycine-like inputs. Alteration of neuronal function in this region also elevates plasma vasopressin levels, contributing to, but not completely accounting for, the hypertension and pulmonary edema observed after destruction of neurons in the region.

Key Words:

• Arterial pressure
• plasma vasopressin
• A1 noradrenergic neurons
• caudal ventrolateral medulla