Hypertension and Exercise

Abstract

A sedentary lifestyle may be a risk factor for hypertension, according to the results of both cross sectional and longitudinal studies. However, exercise may reverse the adverse effects of lack of activity. Many controlled studies have shown that exercise lowers systolic/diastolic blood pressure by at least 10/5 mmHg. Exercise not only improves blood pressure, but also attenuates other risk factors for cardiovascular complications. Dynamic isotonic exercise (e.g., walking) is more effective than static isometric exercise(e.g., weight lifting). Milder (e.g., brisk walking for 30–60 minutes/day) rather than moderate to severe exercise (e.g., running) is also recommended because of similar effectiveness and better compliance. The underlying mechanism of action of exercise on blood pressure seems to be multifactorial involving a decrease in pressor factors such as plasma norepinephrine, the serum Na/K ratio, endogenous ouabain-like substance and erythrocyte mean corpuscular volume, as well as an increase in depressor factors such as plasma prostaglandin E, serum taurine and urinary dopamine excretion.

Key Words:

• Dopamine
• Endogenous ouabain-like substance(EOLS)
• Exercise
• Lactive threshold
• Mean corpuscular volume(MCV)
• Norepinephrine
• Plasma volume
• Prostaglandin E
• Renin
• Taurine