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Review Article

Regulation of DNA glycosylases and their role in limiting disease

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Pages 460-478 | Received 15 Nov 2011, Accepted 05 Jan 2012, Published online: 06 Feb 2012
 

Abstract

This review will present a current understanding of mechanisms for the initiation of base excision repair (BER) of oxidatively-induced DNA damage and the biological consequences of deficiencies in these enzymes in mouse model systems and human populations.

This paper was first published online on Early Online on 1 February 2012.

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