The Effect of Systemic Heparinisation and Haemodialysis on Plasma Octadeca-9,11-Dienoic Acid (9,11-La')

D. G. Wickens Department of Chemical Pathology, Whittington Hospital, London, N19 5NF

J. F. Griffin Department of Chemical Pathology, Whittington Hospital, London, N19 5NF

E. R. Maher Department of Medicine, Charing Cross Hospital, London, W6 8RF, UK

J. R. Curtis Department of Chemical Pathology, Whittington Hospital, London, N19 5NF; Department of Medicine, Charing Cross Hospital, London, W6 8RF, UK

T. L. Dormandy Department of Chemical Pathology, Whittington Hospital, London, N19 5NF; Department of Medicine, Charing Cross Hospital, London, W6 8RF, UK

Abstract

Systemic heparinisation induces a sharp rise not only in plasma total free fatty acids but also in 9.11-LA′ concentration and in the 9,11 -LA′/9,12-LA molar ratio. This “heparin effect” is enhanced by haemodialysis with cuprophan membranes but not with polycarbonate membranes.

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The Effect of Systemic Heparinisation and Haemodialysis on Plasma Octadeca-9,11-Dienoic Acid (9,11-La')

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The Effect of Systemic Heparinisation and Haemodialysis on Plasma Octadeca-9,11-Dienoic Acid (9,11-La')

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